刘成辉 教授（博士生导师）

毕业学校：清华大学（博士）

电     话：029-81530859

电子邮箱：liuch@snnu.edu.cn

研究方向：生化分析及分子诊断

讲授课程：分析化学

人个简介：

    2009年7月于清华大学化学系获理学博士学位。现为陕师大化学化工学院教授，分析化学/化学生物学专业博士生导师。2015年度“陕西省青年科技新星”；2016年获得国家基金委“优秀青年科学基金”资助；2020年获陕西青年科技奖；现担任Wiley出版社ChemistrySelect期刊编委。主要研究兴趣为：（1）生化分析与分子诊断；（2）功能材料表界面传感；（3）单分子与单颗粒分析。先后主持国家自然科学基金等省部级以上项目10项，获陕西省及河北省科学技术奖励3项。作为通讯作者在Angew. Chem. Int. Ed., Nano Lett., Chem. Sci., Anal. Chem., Adv. Funct. Mater.等发表论文70余篇。
    因科研工作需要，课题组常年招聘师资博士后，特别优秀者可直接申报副教授岗位，陕师大正处于快速发展时期，人才引进力度大，待遇优厚，具体情况可邮件联系。热忱欢迎从事微流控芯片分析、功能材料与器件、分子诊断、纳米生物技术等相关领域的同仁加盟合作。

代表性成果：

1. Lijun Zhang, Wenjiao Fan, Dailu Jia, Qinya Feng, Wei Ren, Chenghui Liu*. Microchamber-Free Digital Flow Cytometric Analysis of T4 Polynucleotide Kinase Phosphatase Based on Single Enzyme-to-Single Bead Space-Confined Reaction. Anal. Chem., 2021, 10.1021/acs.analchem.1c03724.

2. Xiaohui Lu^†, Chen Hu^†, Dailu Jia, Wenjiao Fan, Wei Ren*, Chenghui Liu*. Amplification-Free and Mix-and-Read Analysis of Multiplexed MicroRNAs on a Single Plasmonic Microbead. Nano Lett., 2021, 21, 6718-6724.

3. Yan Qi, Yuqing Zhai, Wenjiao Fan, Wei Ren, Zhengping Li, Chenghui Liu*. Click Chemistry-Actuated Digital DNA Walker Confined on a Single Particle toward the Absolute MicroRNA Quantification. Anal. Chem., 2021, 93, 1620-1626.

4. Gaoting Wang, Weimin Tian, Xiaoling Liu*, Wei Ren, Chenghui Liu*. A new CRISPR-derived microRNA sensing mechanism based on Cas12a self-powered and rolling circle transcription (RCT)-unleashed real-time crRNA recruiting. Anal. Chem., 2020, 92, 6702-6708.

5. Xiaohui Lu, Wei Ren, Chen Hu, Chenghui Liu*, Zhengping Li*. Plasmon-Enhanced SERS Mapping Concentrated on a Single Bead for the Ultrasensitive and Multiplexed Immunoassay. Anal. Chem., 2020, 92, 12387-12393.

6. Zhenhao Zhang, Dandan Yang, Weimin Tian, Yan Qi, Wei Ren, Zhengping Li, Chenghui Liu*. Facile Clamp-Assisted Ligation Strategy for Direct Discrimination and Background-Free Quantification of Site-Specific 5‑Formylcytosine. Anal. Chem., 2020, 92, 3477-3482.

7. Ya Li^†, Dailu Jia^†, Wei Ren*, Feng Shi, Chenghui Liu*. A Versatile Photoinduced Electron Transfer-Based Upconversion Fluorescent Biosensing Platform for the Detection of Disease Biomarkers and Nerve Agent. Adv. Funct. Mater., 2019, 29, 1903191.

8. Liping Zhu, Desheng Chen, Xiaohui Lu, Yan Qi, Pan He, Chenghui Liu,* Zhengping Li. An Ultrasensitive Flow Cytometric Immunoassay Based on Bead Surface-Initiated Template-Free DNA Extension. Chem. Sci., 2018, 9, 6605-6613.

9. Wenjiao Fan, Yan Qi, Liying Qiu, Pan He, Chenghui Liu,* Zhengping Li. Click Chemical Ligation-Initiated On-Bead DNA Polymerization for the Sensitive Flow Cytometric Detection of 3´-Terminal 2´-O-Methylated Plant MicroRNA. Anal. Chem., 2018, 90, 5390-5397.

10. Yueying Sun, Yuanyuan Sun, Weimin Tian, Chenghui Liu,* Kejian Gao, Zhengping Li.* A novel restriction endonuclease GlaI for rapid and highly sensitive detection of DNA methylation coupled with isothermal exponential amplification reaction. Chem. Sci., 2018, 9, 1344-1351.