石先莹 教授（博士生导师）

毕业学校：陕西师范大学

电     话：029-81530726

电子邮箱：shixy@snnu.edu.cn

研究方向：绿色催化合成

讲授课程：

人个简介：

    2008年12月份获得工学博士学位，2011年10月至2013年8月，在加拿大麦吉尔大学做访问教授。主要从事高效串联反应、H₂O₂ 选择性氧化等绿色催化合成方面的研究工作，在环境友好反应介质绿色过程替代等方面具有较好的研究积累。目前主持国家自然科学基金面上项目1项、国家重点研发计划子课题1项、陕西师范大学中央高校基本科研业务费科研发展专项1项，参与国家自然科学基金重点项目一项（第二参与人）。主持完成国家自然科学基金2项、陕西省自然科学基金、西安市工业应用技术研究项目等7 项。在 J. Am. Chem. Soc.、Angew Chem. Int. Ed.、Org. Lett.、Adv. Synth. Catal.、Chem.Eur. J.、J. Org. Chem. 等本领域主流学术期刊发表研究论文50余篇，申请中国发明专利10件，其中授权5件，获陕西省高等学校科学技术奖一等奖（2016年，第二完成人）和陕西省科学技术奖二等奖（2016年，第二完成人）。主编《有机化学实验》，编著《过渡金属催化的碳氢键官能团化反应》，参编《有机化学学习指导与习题详解》和《中级有机化学》。研究兴趣：(1) 过氧化氢为氧源的绿色催化氧化反应；(2)过渡金属催化碳氢键活化的高效串联反应。

代表性成果：

[1]  Xin-Ran Li, Si-Qi Chen, Juan Fan, Chao-Jun Li, Xue Wang, Zhong-Wen Liu, Xian-Ying Shi*, Controllable tandem [3+2] cyclization of aromatic aldehydes with maleimides: rhodium(III)-catalyzed divergent synthesis of indane-fused pyrrolidine-2,5-dione, Org. Lett., 2020, 22, 8808−8813.

[2]  Si-Qi Chen, Xin-Ran Li, Chao-Jun Li, Juan Fan, Zhong-Wen Liu, Xian-Ying Shi*, Aldehyde as a traceless directing group for regioselective C−H alkylation catalyzed by rhodium(III) in air, Org. Lett., 2020, 22, 1259−1264.

[3]  Fan Pu, Zhong-Wen Liu, Lin-Yan Zhang, Juan Fan, Xian-Ying Shi*, Switchable C−H alkylation of aromatic acids with maleimides in water: carboxyl as a diverse directing group, ChemCatChem, 2019, 11, 4116–4122

[4]  Jia-Ni Wang, Si-Qi Chen, Zhong-Wen Liu, Xian-Ying Shi*, Divergent syntheses of spiroindanones and 2‑substituted 1‑indanones by ruthenium-catalyzed tandem coupling and cyclization of aromatic acids with α,β-unsaturated ketones, J. Org. Chem., 2019, 84, 1348−1362.

[5]   Wen-Jing Han, Fan Pu, Chao-Jun Li, Zhong-Wen Liu, Juan Fan, Xian-Ying Shi*, Carboxyl-directed conjugate addition of C-H bonds to α,β-unsaturated ketones in air and water,  Adv. Synth. Catal., 2018, 360, 1358−1363.

[6]  Fan Pu, Lin-Yan Zhang, Zhong-Wen Liu, Xian-Ying Shi*, Palladium(II)-catalyzed decarboxylative cross-dehydrogenative coupling: direct synthesis of meta-substituted biaryls from aromatic acids, Adv. Synth. Catal., 2018, 360, 2644−2649.

[7]  Juan Fan, Peng-Min Wang, Jia-Ni Wang, Xue Zhao, Zhong-Wen Liu, Jun-Fa Wei,Xian-Ying Shi*, Ruthenium (II)-catalyzed synthesis of phthalides via the cascade addition and cyclization of aromatic acids with aldehydes, Sci. China Chem., 2018, 61, 153−158.

[8]   Wen-Jing Han, Fan Pu, Juan Fan, Zhong-Wen Liu, Xian-Ying Shi*, Rhodium(III)-catalyzed tandem C−H olefination and oxidative cyclization of aromatic acids with acrylates for the synthesis of (E)-3- ylidenephthalides, Adv. Synth. Catal., 2017, 359, 3520−3525.

[9]  Peng-Min Wang, Fan Pu, Ke-Yan Liu, Chao-Jun Li, Zhong-Wen Liu, Xian-Ying Shi*, Juan Fan, Ming-Yu Yang, Jun-Fa Wei, Catalyst-free three-component tandem CDC cyclization: convenient access to isoindolinones from aromatic acid, amides, and DMSO by a pummerer-type rearrangement, Chem. Eur. J., 2016, 22, 6262−6267.

[10]  Xian-Ying Shi*, Wen-Jing Han, Chao-Jun Li*, Transition-metal-catalyzed direct addition of aryl C–H bonds to unsaturated electrophiles, Chem. Rec., 2016, 16, 1178−1190.

[11] Juan Fan, Fan Pu, Man Sun, Zhong-Wen Liu, Xiao-Yan Han, Jun-Fa Wei, Xian-Ying Shi*, Immobilized bis-layered ionic liquids/peroxotungstates as an efficient catalyst for selective oxidation of alcohols in neat water, New J. Chem., 2016, 40, 10498−10503.

[12] Xian-Ying Shi*, Ke-Yan Liu, Juan Fan, Xue-Fen Dong, Jun-Fa Wei, Chao-Jun Li*, A convenient synthesis  of N-aryl benzamides by rhodium-catalyzed ortho-amidation and decarboxylation of benzoic acids, Chem. Eur. J., 2015, 21, 1900−1903.

[13] Xian-Ying Shi*, Man Sun, Juan Fan, Peng-Min Wang, Wen-Juan Ma, Jun-Fa Wei*, Deep oxidative desulfurization of benzothiophene and dibenzothiophene with a peroxophosphotungstate–ionic liquid brush assembly, Appl. Organometal. Chem., 2015, 29,     633−637.

[14] Xian-Ying Shi*, Xue-Fen Dong, Juan Fan, Ke-Yan Liu, Jun-Fa Wei, Chao-Jun Li*, Ru(II)-catalyzed ortho-amidation and decarboxylation of aromatic acids: a versatile route to meta-substituted N-aryl benzamides, Sci. China. Chem., 2015, 58, 1286−1291.

[15] Xian-Ying Shi, Andrea Renzetti, Soumen Kundu, Chao-Jun Li*, A rhodium-catalyzed cascade cyclization: direct synthesis of N-substituted phthalimides from isocyanates and benzoic acids, Adv. Synth. Catal., 2014, 356, 723–728.

[16] Xian-Ying Shi, Chao-Jun Li*, Synthesis of indene frameworks via rhodium-catalyzed cascade cyclization of aromatic ketone and unsaturated carbonyl compounds, Org. Lett., 2013, 15, 1476–1479.

[17] Xian-Ying Shi, Chao-Jun Li*, A novel Rhodium-catalyzed cascade cyclization: direct synthesis of 3-substituted phthalides from aldehydes and aromatic acids, Adv. Synth. Catal., 2012, 354, 2933–2938. (Highlighted by Synfacts 2013, 9(5), 0082).